AppleSlim - Weight Loss & Heart Health

Certified Naturals AppleSlim™ is a natural supplement containing the world's leading apple polyphenols ingredient for use in a weight management program and for cardiovascular support.

AppleSlim

 

AppleSlim contains the patented apple polyphenol ingredient - ApplePhenon™ together with green coffee bean extract. 

ApplePhenon apple polyphenols are powerful plant-based antioxidants that have been the subject of human clinical trials for a wide variety of health issues:

  • Weight management for visceral fat and overall weight
  • Cardiovascular support (cholesterol and triglyceride management)
  • Glucose management
  • Athletic performance
  • Respiratory support
  • Skin care
  • Dental care
  • Inflammatory conditions

 

Apples and green coffee beans

AppleSlim utilizes two ingredients that make it the ideal supplement for use in a weight management program. It combines ApplePhenon, a patented, clinically proven apple polyphenol ingredient together with green coffee bean extract. Apples and coffee beans. Two common everyday foods – but AppleSlim contains unique concentrated versions of these foods.

 

How it Works

ApplePhenon is thought to have three primary modes of action to deliver its benefits for weight management and cardiovascular support:

  1. Its role as an antioxidant (clearing waste from the cells and protecting them from damage).

  2. Its prebiotic properties which promote improved gut flora.

  3. Its ability to mimic a calorie-restricted diet by inhibiting enzyme activity in lipid (fat) and glucose absorption.


 

Confirmed by Clinical Studies

Two clinical studies have shown that daily doses of 600 mg of ApplePhenon can help to reduce visceral fat and overall weight.

 
The first 12-week placebo-controlled study demonstrated that by using ApplePhenon, visceral fat in overweight individuals could be decreased by 9% while reducing waistline and hip measurements.

A second longer study showed a reduction in visceral fat area, an improvement in adiponectin levels (anti-inflammatory hormone that helps with glucose control) and a decrease in overall weight.

 

How it's Made

ApplePhenon is carefully extracted from specially selected wildcrafted immature green apples from Central Asia, the “Land of the Original Apple”. Using a proprietary gentle extraction process, the highest concentration of apple polyphenols is preserved for optimal antioxidant activity. A daily dose of AppleSlim capsules containing ApplePhenon ingredient contains the equivalent polyphenols of 18 ripe apples.

 

18 apples in each dose

 

 

Clinical Research

Weight Management (reduction of visceral fat) Two clinical studies have shown that daily doses of 600 mg of ApplePhenon™ can help to reduce visceral fat and overall weight. The first 12-week placebo-controlled study demonstrated that by using ApplePhenon™, visceral fat in overweight individuals could be reduced by 9% while slimming waistline by 1.7 cm and hip measurement by 0.8 cm.(6) A second longer study showed a reduction in visceral fat area, an improvement in adiponectin levels (anti-inflammatory hormone that helps with glucose control) and 1.5 lb decrease in overall weight.(7)
Cardiovascular Support (cholesterol and triglyceride) A 12-week study of moderately obese subjects was conducted with a dose of 600 mg of ApplePhenon™ vs hops extract and a placebo. Patients on the ApplePhenon™ polyphenols were able to reduce total cholesterol and LDL (“bad cholesterol”) levels while improving HDL (“good cholesterol”) levels.(8) This corroborated an earlier 4-week pilot study that had indicated similar results.(9) Another study done with 600 mg of ApplePhenon™ showed that the absorption of triglycerides from a high fat diet could be reduced significantly by apple polyphenols’ ability to inhibit pancreatic lipase activity.(10)
Glucose Management A randomized, double-blind placebo-controlled study with 65 patients using a dose of 600 mg of ApplePhenon™ was conducted. It showed that ApplePhenon™ could improve impaired glucose tolerance vs. a placebo over a 12-week period. The researchers concluded that insulin response was increased due to a reduction in inflammation and improvement in gut microbiota.(11)
Athletic Performance An eight-day study of college athletes was conducted using a dose of 1,200 mg of ApplePhenon™. ApplePhenon™ significantly improved athletic performance and fatigue resistance vs. ascorbic acid (1,000 mg), as measured by bicycle exercise load testing.(12)
Respiratory Support Low doses of ApplePhenon™ (50-200 mg daily) have been shown to reduce the symptoms of allergic rhinitis. Patients with chronic rhinitis in the double-blind study showed improvement in sneezing attacks, reduced nasal discharge and nasal swelling.(13)
Skin Care Researchers studied ApplePhenon™’s benefits for skin-related allergic reactions. They noted that at 600 mg daily, atopic dermatitis conditions were improved with less inflammation, cracking and itching, along with fewer associated sleeping interruptions.(14)

 

 

Recommended Use

Could complement a healthy lifestyle that incorporates a calorie-reduced diet and regular physical activity for individuals involved in a weight management program. Helps maintain healthy blood pressure levels. Helps support cardiovascular health. Source of antioxidants that help protect against cell damage caused by free radicals.

Ingredients

 Each AppleSlim capsule contains:

ApplePhenon Apple Polyphenols (70% polyphenols) (Malus domestica)

200 mg

Green Coffee Bean Extract (47.5% chlorogenic acids; 2% caffeine)

135 mg

Non-medicinal ingredients: Microcrystalline cellulose, colloidal silicon dioxide, vegetable grade magnesium stearate and hypromellose (vegetable capsule).

Recommended dose: 
Adults: Take 1 capsule, 3 times per day.

Cautions and Warnings: 
Consult a health care practitioner/health care provider/health care professional/doctor/physician prior to use if you are breastfeeding.

Contra-Indications: 
Do not use this product if you are pregnant.

KEEP OUT OF THE REACH OF CHILDREN.
Do not use if outer safety seal is broken.

 

Free from animal derivatives, artificial colours, artificial flavours, corn, gluten, wheat, lactose, dairy, preservatives, soy, added sugar, yeast and GMO materials.

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References

1. Watanabe, Takuya et al. Coffee Abundant in Chlorogenic Acids Reduces Abdominal Fat in Overweight Adults: A Randomized, Double-Blind, Controlled Trial. Nutrients. 2019 Jul; 11(7): 1617. Published online 2019 Jul 16. doi: 10.3390/nu11071617
2. Revuelta-Iniesta, R. and E. A. S. Al-Dujaili. Consumption of Green Coffee Reduces Blood Pressure and Body Composition by Influencing 11β-HSD1 Enzyme Activity in Healthy Individuals: A Pilot Crossover Study Using Green and Black Coffee. Biomed Res Int. 2014; 2014: 482704. Published online 2014 Jul 16. doi: 10.1155/2014/482704
3. Dellalibera SSA O. et al. SvetolR, green coffee extract, induces weight loss and increases the lean to fat mass ratio in volunteers with overweight problem. Ospedale SS. Antonio e Margherita, Dipartimento Medico-Ambulatorio Obesita, Tortona, Italy •BerkemR, Le Marais ouest, BP 4, 24 680 Gardonne, France.
4. Thom. E., The Effect of Chlorogenic Acid Enriched Coffee on Glucose Absorption in Healthy Volunteers and Its Effect on Body Mass When Used Long-term in Overweight and Obese People. The Journal of International Medical Research.
5. Masumoto S, Terao A, Yamamoto Y, Mukai T, Miura T, Shoji T. Non-absorbable apple procyanidins prevent obesity associated with gut microbial and metabolomic changes. Sci Rep. 2016 Aug 10; 6:31208.
6. Akazome Y, Kametani N, Kanda T, Shimasaki H, Kobayashi S. Evaluation of safety of excessive intake and efficacy of long-term intake of beverages containing apple polyphenols. J Oleo Sci. 2010; 59(6):321-38.
7. Nagasako-Akazome Y1, Kanda T, Ohtake Y, Shimasaki H, Kobayashi T. Apple polyphenols influence cholesterol metabolism in healthy subjects with relatively high body mass index. J Oleo Sci. 2007; 56(8):417-28.
8. Nagasako-Akazome Y, Kanda T, Ikeda M, Shimasaki H. Serum Cholesterol-Lowering Effect of Apple Polyphenols in Healthy Subjects. J Oleo Sci. 2005; 54(3): 143-151.
9. Nagasako-Akazome Y, Kanda T, Ohtake Y, Shimasaki H, Kobayashi T. Apple polyphenols influence cholesterol metabolism in healthy subjects with relatively high body mass index. J Oleo Sci. 2007; 56(8):417-28.
10. Sugiyama H, Akazome Y, Shoji T, Yamaguchi A, Yasue M, Kanda T, Ohtake Y.Oligomeric procyanidins in apple polyphenol are main active components for inhibition of pancreatic lipase and triglyceride absorption. J Agric Food Chem. 2007 May; 30;55(11):4604-9.
11. Shoji T, Yamada M, Miura T, Nagashima K, Ogura K, Inagaki N, Maeda-Yamamoto M. Chronic administration of apple polyphenols ameliorates hyperglycaemia in high-normal and borderline subjects: A randomised, placebo-controlled trial. Diabetes Res Clin Pract. 2017 Jul; 129:43-51.
12. Ataka S, Tanaka M, Nozaki S, Mizuma H, Mizuno K, Tahara T, et al. Effects of Applephenon(R) and ascorbic acid on physical fatigue. Nutrition 2007;23:419 –23.
11. Enomoto, T., Nagasako-Akazome, Y., Kanda, T., Ikeda, M., Dake, Y. (2006). “Clinical effects of apple polyphenols on persistent allergic rhinitis: A randomized double-blind placebo 22 controlled parallel arm study.” Journal of Investigative Allergology and Clinical Immunology 2006;16(5):283-9.
12. Kojima, T., Akiyama, H., Sasai, M. et al. Anti-allergic effect of apple polyphenol on patients with atopic dermatitis: A pilot studyAllergol Int. 2000 49(1):69-73.